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AlterNet -- How Does Pot Work? The places in the body with THC receptors seem to correspond with the drug's effects, though not always. "One of the key areas in the [brain's] frontal cortex has a high density of [such] receptors," says Iversen, "and that may have something to do with impairment in what brain scientists call 'executive' functions -- short-term memory, learning, the ability to take in information, plan ahead, make complicated future arrangements. That ties in reasonably well with actual experience," he adds dryly.